About

The company Irene Nanocore Solutions was started by Dr. S. Sundar Manoharan and Dr. T.R. Muralitharan  in late 2009.

Dr. S.Sundar Manoharan is a professor at Indian Institute of Technology in Department of Chemistry and Samtel center for display technology.Dr. Manoharan has over 12 years of extensive experience in teaching and research in physical chemistry.

Dr. T.R.Muralidharan  is a professor in cardiology at Shri Ramchandra Medical College and Research Institute,Chennai. He specializes in interventional Cardiology emphasizing on Electro- Physiology.

The directors for the Irene Nanocore Solutions are Mrs. Sheba Manoharan and Mrs. Geetha Muralitharan.

Company

Irene Nanocore Solutions is an Research and Development firm in the field of nanotechnology. The Company’s main focus is to present novel ideas based on principles of nanotechnology.

Motivation

Currently coronary stents are used in more than 90% of PCI procedures world wide for treatment of Coronary artery disease.

 The dramatic increase in the use of Bare Metal Stents identified a new problem, restenosis occurring within the stent, In-stent restenosis(ISR).    ISR is clearly correlated with the degree of stent-induced injury to the vessel wall, strut thickness, patient factors (diabetes, acute coronary syndromes, etc.), and lesion characteristics (small luminal diameter vessel, bifurcation, ostial, restenotic as well as venous graft lesions). In addition, chronic foreign-body inflammatory response as well as gradual long-term corrosion of the metallic stent may have roles in the process of ISR.  Drug eluting stents (DES) have reduced ISR and target lesion revascularization (TLR) compared with BMS and launched a revolution in the interventional treatment of symptomatic CAD.  However, enthusiasm for this technology has recently been dampened by concerns about late stent thrombosis (LST), incomplete endo- thelialization, coronary artery spasm, and abnormal vasomotor function. Thus, focus has been brought onto the structure and composition of stents and stent coatings with particular interest in how the vessel responds to the foreign device and development of devices with improved biocompatibility and long-term patient outcomes.

Research

Projects

Contact Us

INCS is located in the SIDBI Incubating Centre, IIT Kanpur, Uttar Pradesh.

Feel free to Call us at : 91-512-259-7425

91-512-259-6043

Or Fax us at                  :  01-512-259-7425/7436

Or email us at              :   ssundar@gmail.com

or                                     :   muralitharantr@gmail.com